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Research

Our faculty and fellows conduct research to improve knowledge, understanding and treatment of kidney disease in children, but are also looking for new ways to measure and improve quality of life in children with the disease.

The division works with the Center for Medicare & Medicaid Services evaluating the quality of care for pediatric hemodialysis patients nationwide in the End Stage Renal Disease Clinical Performance Measures (CPM) Project. New findings from this research partnership have increased our understanding of the effects that factors such as anemia, nutrition, dialysis dose and type have on disease outcome. It has also highlighted the need to address racial and ethnic disparities in the delivery of renal-replacement therapy.

In addition, the division works with national and international data registries, including the North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) and the International Pediatric Peritoneal Dialysis Network (IPPN) with the goal of improving clinical outcomes in children with chronic kidney disease.

Dr. Fivush’s interests have been dominated by her concern for children with chronic kidney disease. She has studied the response of the children to standard childhood immunizations, and has been instrumental in setting the standards for vaccinating children on dialysis or children with kidney transplants.  She also is keenly interested in quality-of-life issues in children with chronic kidney disease, and over the last 10 years has worked to develop research instruments that measure quality of life in such patients.

Dr. Furth  is a Principal Investigator for the NIH-funded Chronic Kidney Disease in Children (C-KID) study, a nationwide effort following 400 children with renal insufficiency for 4 years in an effort to identify factors which affect the progression of kidney disease. Such knowledge could point to new therapies to slow the progression of kidney disease to its end-stage forms.

Dr. Neu  is involved in vaccine research and is also doing research on quality improvement in pediatric end-stage renal disease.

Dr. Fadrowski  studies heavy metal exposure and its effects on kidney disease; anemia in children with kidney disease and quality improvement in children with end-stage forms of the disease.

Dr. Atkinson studies anemia in children with chronic kidney disease as well as disparities in access to health care and outcomes in minority children with end-stage kidney disease.

Dr. Gerson studies adherence to treatment and quality of life in children with kidney disease.

Dr. Sule, a pediatric rheumatologist, studies pediatric systemic lupus erythematosus and biomarkers of this often-evasive and hard-to-diagnose condition.

 


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